Functional Mechanisms

Ideas from the
bench & beyond

Translational biomedical writing on microbiology, mechanism, scientific communication, medical affairs, and AI-enabled evidence generation.

Why Most Antimicrobial Data Fails at Translation

Why Most Antimicrobial Data Fails at Translation

February 2026 // Platform Thinking // R&D Strategy

In antimicrobial R&D, we're often drowning in data but starving for actionable evidence. We celebrate "hits" in the lab—zones of inhibition, promising MICs—then watch them evaporate when exposed to the biophysics of real membranes, the kinetics of real protein binding, and the ecology of real infections.

Why Most Antimicrobial Data Fails at Translation

Why Most Antimicrobial Data Fails at Translation February 2026 // Platform Thinking // R&D Strategy In an...